Successful treatment of pyoderma gangrenosum with intravenous immunoglobulins during pregnancy

J Cutan Med Surg. 2012 May-Jun;16(3):205-7. doi: 10.1177/120347541201600314.

Abstract

Background: Pyoderma gangrenosum is a rare ulcerative skin disease usually starting with a pustular lesion that rapidly progresses to painful ulcers with undermined violaceous borders. Numerous associated disorders have been described, including inflammatory bowel disease, rheumatologic or hematologic disorders, chronic active hepatitis, and malignancies. The occurrence of pyoderma gangrenosum during pregnancy is uncommon.

Objective: We report a case of a patient with an aggravation of preknown pyoderma gangrenosum during pregnancy who was successfully treated with intravenous immunoglobulins.

Conclusion: Administration of immunoglobulins represents a safe and effective treatment option for this subset of patients, as demonstrated in the present case.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use*
  • Pregnancy
  • Pregnancy Complications / drug therapy*
  • Pyoderma Gangrenosum / drug therapy*

Substances

  • Immunoglobulins, Intravenous