Near-infrared center-of-intensity time gated imaging for detection of a target in a highly scattering turbid medium

Technol Cancer Res Treat. 2012 Aug;11(4):309-15. doi: 10.7785/tcrt.2012.500279. Epub 2012 Jun 15.

Abstract

A near-infrared optical imaging approach for locating a target embedded in a turbid medium is introduced. The target localization is based on an analysis of the spatial variation of the transmitted-light intensity distribution for illumination at different positions on the sample boundary. The approach is used to detect, locate and generate images of absorbing targets embedded inside model scattering media of thickness approximately 50 times the transport mean free path of the medium, as well as, of ex vivo biological tissue specimens.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Diagnostic Imaging / methods*
  • Emulsions / chemistry
  • Humans
  • Infrared Rays*
  • Liver
  • Models, Biological
  • Nephelometry and Turbidimetry
  • Phospholipids / chemistry
  • Scattering, Radiation*
  • Solutions / chemistry
  • Soybean Oil / chemistry
  • Sus scrofa

Substances

  • Emulsions
  • Phospholipids
  • Solutions
  • soybean oil, phospholipid emulsion
  • Soybean Oil