Abstract
The new and easily prepared OTips-DalPhos ligand (L1) offers broad substrate scope at relatively low loadings in the palladium-catalyzed C-N cross-coupling/cyclization of o-alkynylhalo(hetero)arenes with primary amines, affording indoles and related heterocyclic derivatives in high yield.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amines / chemistry
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Catalysis
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Cyclization
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Indoles / chemical synthesis*
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Indoles / chemistry
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Ligands
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Molecular Conformation
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Palladium / chemistry*
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Phosphines / chemical synthesis*
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Phosphines / chemistry
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Silanes / chemical synthesis*
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Silanes / chemistry
Substances
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Amines
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Indoles
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Ligands
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Phosphines
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Silanes
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Palladium