The physiology of cardiac calcium handling

Nils Bögeholz; Adam Muszynski; Christian Pott

doi:10.1007/s10354-012-0102-3

The physiology of cardiac calcium handling

Wien Med Wochenschr. 2012 Jul;162(13-14):278-82. doi: 10.1007/s10354-012-0102-3. Epub 2012 Jun 16.

Authors

Nils Bögeholz¹, Adam Muszynski, Christian Pott

Affiliation

¹ Division of Clinical and Experimental Rhythmology, Department of Cardiology and Angiology, University Hospital Münster, Münster, Germany. nils.boegeholz@googlemail.com

PMID: 22707075
DOI: 10.1007/s10354-012-0102-3

Abstract

Cardiac calcium (Ca(2+)) handling subsumes the mechanisms maintaining the myocardial Ca(2+) homeostasis that contribute essentially to cardiac performance. This review addresses the interaction of transplasmalemmal and transsarcoplasmic Ca(2+) flux, its potential modifications due to β-adrenergic stimulation and its implications on cardiac action potential.

Publication types

Review

MeSH terms

Calcium / metabolism*
Calcium Channels / physiology*
Electrocardiography
Heart Conduction System / physiology
Heart Diseases / physiopathology*
Heart Rate / physiology
Homeostasis / physiology
Humans
Myocardial Contraction / physiology
Myocardium / metabolism*
Receptors, Adrenergic, beta / physiology
Sarcoplasmic Reticulum / physiology
Sarcoplasmic Reticulum Calcium-Transporting ATPases / physiology
Sodium-Calcium Exchanger / physiology

Substances

Calcium Channels
Receptors, Adrenergic, beta
Sodium-Calcium Exchanger
Sarcoplasmic Reticulum Calcium-Transporting ATPases
Calcium