Emergence of an SGI1-bearing Salmonella enterica serotype Kentucky isolated from septic poultry in Nigeria

J Infect Dev Ctries. 2012 Jun 15;6(6):483-8. doi: 10.3855/jidc.1988.

Abstract

Introduction: Salmonella enterica serotype Kentucky was isolated from septic poultry in Nigeria. The objective of this study was to characterize this isolate by screening for SGI1 and hyper-virulence.

Methodology: The strain was characterized by identification of Salmonella genomic island 1 (SGI1) through a PCR assay and we used a tissue culture invasion assay to assess protozoa-mediated hyper-invasion.

Results: Salmonella genomic island 1 (SGI1) was identified in the strain along with an SGI1 gene (SO13) implicated in hyper-virulence. Protozoa-mediated hyper-invasiveness was also documented in the strain.

Conclusion: The hyper-invasion is concordant with this emerging strain's ability to cause fowl paratyphoid.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Endocytosis
  • Genomic Islands*
  • Nigeria / epidemiology
  • Polymerase Chain Reaction
  • Poultry
  • Poultry Diseases / epidemiology*
  • Poultry Diseases / microbiology*
  • Salmonella Infections, Animal / epidemiology*
  • Salmonella enterica / classification*
  • Salmonella enterica / genetics*
  • Salmonella enterica / isolation & purification
  • Salmonella enterica / pathogenicity
  • Tetrahymena / microbiology
  • Virulence
  • Virulence Factors / genetics

Substances

  • Virulence Factors