The dysplastic nevus: from historical perspective to management in the modern era: part I. Historical, histologic, and clinical aspects

J Am Acad Dermatol. 2012 Jul;67(1):1.e1-16; quiz 17-8. doi: 10.1016/j.jaad.2012.02.047.

Abstract

Since its description in the 1970s, the dysplastic nevus has been a source of confusion, and whether it represents a precursor to melanoma remains a controversial subject. Although a Consensus Conference in 1992 recommended that the term "dysplastic nevus" no longer be used, the histologic diagnosis continues to present a therapeutic quandary for dermatologists and other physicians, and there remains significant variation in clinical management. In part I of this continuing medical education review, we will discuss the historical origins of the term, the evidence for its distinct histologic basis, and its clinical significance.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Dysplastic Nevus Syndrome* / diagnosis
  • Dysplastic Nevus Syndrome* / genetics
  • Dysplastic Nevus Syndrome* / pathology
  • Humans
  • Melanoma / genetics
  • Risk Factors
  • Skin Neoplasms / genetics
  • Terminology as Topic