Abstract
Bis-arylsulfide BODIPY systems were prepared and studied for multiple O-atom sensing (at 522 nm); 2- and 3-atom loading was optimal (50-fold, "turn on"). Neuronal studies showed greater H(2)O(2) sensitivity than 2',7'-dichlorofluorescein diacetate. The novel 1,3,6-trimethyl BODIPY formed as a biproduct under Lindsey conditions.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Boron Compounds / chemistry*
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Cell Line, Tumor
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Chlorobenzoates / chemistry
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Copper / chemistry
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Crystallography, X-Ray
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Fluorescent Dyes / chemistry
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Humans
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Hydrogen Peroxide / analysis*
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Magnetic Resonance Spectroscopy
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Microscopy, Fluorescence*
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Molecular Conformation
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Neurons / metabolism
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Oxidation-Reduction
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Oxygen / chemistry*
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Sulfur / chemistry*
Substances
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4,4-difluoro-4-bora-3a,4a-diaza-s-indacene
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Boron Compounds
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Chlorobenzoates
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Fluorescent Dyes
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Sulfur
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Copper
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Hydrogen Peroxide
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3-chloroperbenzoic acid
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Oxygen