Modelling the epidemiological impact of scaling up HIV testing and antiretroviral treatment in China

Sex Health. 2012 Jul;9(3):261-71. doi: 10.1071/SH11104.

Abstract

Background: The HIV epidemic in China has been increasing. In response, a 5-year action plan in China has prioritised the scale-up of HIV testing and treatment.

Methods: We use a mathematical model to reproduce HIV epidemic trends in China and to forecast epidemic trends according to current conditions or increases in the rate of HIV testing or roll-out of antiretroviral therapy.

Results: We show that the epidemic in China could be expected to experience a 2.5-fold expansion over the next 5 years such that ~1.8 million people will be infected with HIV in China by 2015. However, increasing testing and treatment rates can have substantial epidemiological benefits. For example, a four-fold increase in testing rates may avert more than 42000 HIV infections and 11000 deaths over the next 5 years. A 10-fold increase in the treatment rate could decrease the number of HIV-related deaths by 58% and the number of new infections by one-quarter by 2015.

Conclusions: Increasing HIV testing and treatment are important public health strategies for prevention.

MeSH terms

  • Anti-Retroviral Agents / therapeutic use
  • China / epidemiology
  • Epidemiologic Studies
  • Female
  • HIV Infections / drug therapy
  • HIV Infections / epidemiology*
  • HIV Infections / prevention & control*
  • HIV Infections / transmission
  • HIV Seroprevalence / trends*
  • Health Promotion / organization & administration
  • Health Promotion / trends*
  • Health Services Accessibility / statistics & numerical data
  • Health Services Accessibility / trends*
  • Humans
  • Incidence
  • Male
  • Mass Screening / statistics & numerical data
  • Models, Statistical
  • Population Surveillance
  • Unsafe Sex / statistics & numerical data

Substances

  • Anti-Retroviral Agents