Effects of oral hyposensitization therapy with nickel on haemoglobin and haematocrit values in sensitized patients

Int J Immunopathol Pharmacol. 2012 Apr-Jun;25(2):519-21. doi: 10.1177/039463201202500223.

Abstract

Nickel deficiency leads to reduced iron content in organs and to reduced hemoglobin levels and haematocrit counts. We carried out a clinical trial of oral hyposensitization therapy with low doses of nickel on a group of 20 patients affected by systemic allergy to this sensitizer element and with a chronic relapsing low hemoglobin level and haematocrit count. We obtained interesting results on maintaining these values in treated patients.

Publication types

  • Letter

MeSH terms

  • Administration, Oral
  • Biomarkers / blood
  • Desensitization, Immunologic* / adverse effects
  • Hematocrit*
  • Hemoglobins / metabolism*
  • Humans
  • Hypersensitivity / blood
  • Hypersensitivity / diagnosis
  • Hypersensitivity / immunology
  • Hypersensitivity / therapy*
  • Maryland
  • Nickel / administration & dosage*
  • Nickel / adverse effects
  • Nickel / immunology*
  • Patch Tests
  • Time Factors
  • Treatment Outcome

Substances

  • Biomarkers
  • Hemoglobins
  • nickel sulfate
  • Nickel