A new acylated flavonol glycoside from the aerial parts of Cardamine tangutorum

J Asian Nat Prod Res. 2012;14(8):805-10. doi: 10.1080/10286020.2012.692363. Epub 2012 Jun 14.

Abstract

A new acylated flavonol glycoside, kaempferol-3-O-β-D-(2-feruloylglucopyranosyl) (1 → 6)-[β-D-glucopyranosyl(1 → 2)]-β-D-glucopyranoside, named tangutorumoside A (1), together with 12 known compounds, was isolated from 50% acetone extract of Cardamine tangutorum. Their structures were elucidated by NMR and MS experiments. In addition, compound 1 could promote the proliferation of splenic lymphocytes and thymic lymphocytes with ConA in vitro.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cardamine / chemistry*
  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification*
  • Drugs, Chinese Herbal / pharmacology
  • Flavonols / chemistry
  • Flavonols / isolation & purification*
  • Flavonols / pharmacology
  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Glycosides / pharmacology
  • Lymphocytes / drug effects
  • Lymphocytes / metabolism
  • Mice
  • Mice, Inbred BALB C
  • Molecular Structure
  • Spleen / cytology
  • Spleen / drug effects
  • Thymus Gland / cytology
  • Thymus Gland / drug effects

Substances

  • Drugs, Chinese Herbal
  • Flavonols
  • Glycosides
  • tangutorumoside A