Breast fibromatosis response to tamoxifen: dynamic MRI findings and review of the current treatment options

J Radiol Case Rep. 2012 Mar;6(3):16-23. doi: 10.3941/jrcr.v6i3.897. Epub 2012 Mar 1.

Abstract

Breast fibromatosis is a rare entity responsible for 0.2% of all solid breast tumors. It has been associated with scars, pregnancy, implants, and familial adenomatous polyposis. We present an interesting case of breast fibromatosis in a 29 year old woman which encroached upon her saline implant and subsequently filled its cavity once the implant was removed. The patient was put on tamoxifen therapy and at 14 month follow-up there was a significant decrease in the size of the mass. Dynamic MRI images are offered for review and current treatment options are discussed.

Keywords: Breast fibromatosis; Dynamic MRI; desmoid; tamoxifen.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Agents, Hormonal / therapeutic use*
  • Breast Neoplasms / diagnostic imaging
  • Breast Neoplasms / drug therapy*
  • Breast Neoplasms / pathology*
  • Female
  • Fibroma / diagnostic imaging
  • Fibroma / drug therapy*
  • Fibroma / pathology*
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Mammography
  • Tamoxifen / therapeutic use*

Substances

  • Antineoplastic Agents, Hormonal
  • Tamoxifen