A bilaterally recurring exophytic mass on the lower jaw

BMJ Case Rep. 2011 Jul 28:2011:bcr0920103362. doi: 10.1136/bcr.09.2010.3362.

Abstract

Brown tumour is a rare focal giant-cell lesion that arises as a direct result of the effect of parathyroid hormone on bone tissue in patients with hyperparathyroidism (HPT). The lesions localise in areas of intense bone resorption, and the bone defect becomes filled with fibroblastic tissue. It can affect the mandible, maxilla, clavicle, ribs and pelvic bones. Therefore, diagnosis requires a systemic investigation for lesion differentiation. The authors present a case of a 27-year-old woman, with a rare case of brown tumour of mandible due to HPT secondary to osteomalacia. The lesion showed a tendency to recur even after excision till her parathyroid levels became normal.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Biopsy, Fine-Needle
  • Diagnosis, Differential
  • Female
  • Granuloma, Giant Cell / diagnosis
  • Granuloma, Giant Cell / etiology*
  • Granuloma, Giant Cell / surgery
  • Humans
  • Hyperparathyroidism / complications*
  • Hyperparathyroidism / diagnosis
  • Hyperparathyroidism / etiology*
  • Hyperparathyroidism / surgery
  • Mandibular Diseases / diagnosis
  • Mandibular Diseases / etiology*
  • Mandibular Diseases / surgery
  • Neoplasm Recurrence, Local
  • Osteomalacia / complications*
  • Radiography, Panoramic
  • Ultrasonography, Interventional