Encapsulated insular carcinoma of the thyroid arising in graves' disease: report of a case and review of the literature

Int J Surg Pathol. 2012 Dec;20(6):636-9. doi: 10.1177/1066896912449688. Epub 2012 Jun 10.

Abstract

Insular carcinoma represents a rather rare form of thyroid cancer. Total encapsulation and history of hyperthyroidism are even extremely rarer events with only a few cases reported in the literature. This article reports an insular carcinoma of the thyroid in a 51-year-old woman, displaying these features and pulmonary metastasis with no cervical lymph node involvement.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenocarcinoma, Follicular / complications
  • Adenocarcinoma, Follicular / metabolism
  • Adenocarcinoma, Follicular / secondary*
  • Adenocarcinoma, Follicular / therapy
  • Calcitonin / metabolism
  • Carcinoma, Medullary / diagnosis
  • Combined Modality Therapy
  • Diagnosis, Differential
  • Female
  • Graves Disease / complications
  • Graves Disease / pathology*
  • Graves Disease / therapy
  • Humans
  • Hyperthyroidism / etiology
  • Hyperthyroidism / pathology
  • Hyperthyroidism / therapy
  • Iodine Radioisotopes / therapeutic use
  • Lung Neoplasms / secondary
  • Middle Aged
  • Neck Dissection
  • Thyroglobulin / metabolism
  • Thyroid Neoplasms / complications
  • Thyroid Neoplasms / metabolism
  • Thyroid Neoplasms / pathology*
  • Thyroid Neoplasms / therapy
  • Thyroidectomy

Substances

  • Iodine Radioisotopes
  • Calcitonin
  • Thyroglobulin