Fluorinated graphene for promoting neuro-induction of stem cells

Adv Mater. 2012 Aug 16;24(31):4285-90. doi: 10.1002/adma.201200846. Epub 2012 Jun 12.

Abstract

Surface engineering of substrates offers the possibility of controlling the physiological functions of cells at the molecular level. Fluorinated graphene promotes the differentiation of MSCs towards neuronal lineages. Cell alignment using printed polydimethylsiloxane channel arrays on fluorinated graphene further enhances the neuro-induction of MSCs even in the absence of chemical inducers.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Differentiation
  • Cells, Cultured
  • Dimethylpolysiloxanes / chemistry
  • Graphite / chemistry*
  • Halogenation
  • Humans
  • Mesenchymal Stem Cells / cytology*
  • Neurons / cytology
  • Surface Properties
  • Tissue Engineering

Substances

  • Dimethylpolysiloxanes
  • baysilon
  • Graphite