Abstract
The prognosis of patients with chronic respiratory tract infections, especially diffuse panbronchiolitis, is remarkably improved by long-term administration of low-dose macrolides. However, in some cases, patients are refractory to macrolide treatment and show a low or no response; therefore, new treatment strategies are required. Here we present a patient refractory to either single low-dose clarithromycin or azithromycin but responded remarkably to the combination usage of both macrolides.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / administration & dosage
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Azithromycin / administration & dosage*
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Clarithromycin / administration & dosage*
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Drug Therapy, Combination
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Female
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Humans
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Immunologic Factors / administration & dosage
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Middle Aged
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Pseudomonas Infections / drug therapy*
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Pseudomonas aeruginosa*
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Respiratory Tract Infections / drug therapy*
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Treatment Outcome
Substances
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Anti-Bacterial Agents
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Immunologic Factors
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Azithromycin
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Clarithromycin