Severe unilateral corneal melting after uneventful phacoemulsification cataract surgery

Clin Exp Optom. 2013 Jan;96(1):109-11. doi: 10.1111/j.1444-0938.2012.00750.x. Epub 2012 Jun 11.

Abstract

We present a rare case of severe unilateral corneal melt after uneventful phacoemulsification. A 38-year-old woman presented one week after uneventful phacoemulsification cataract surgery complaining of pain and blurred vision in her operated eye. Our differential diagnosis included peripheral ulcerative keratitis, Mooren's ulcer and herpetic keratitis. The patient was started on oral acyclovir and topical steroids. An extensive blood work-up was done to rule out autoimmune diseases. Purified protein derivative test demonstrated 15 mm of erythema. Because the clinical picture was progressing, the patient was started on triple anti-tuberculosis therapy. Despite treatment, the patient was complaining of excruciating eye pain that was relieved only with intramuscular prednisone injections. The corneal melt healed after approximately three months without any other intervention, leaving a 90 per cent thickness loss in its central area. Idiopathic corneal melt after uneventful phacoemulsification is a rare complication, which must be managed in a multidirectional treatment approach to prevent devastating corneal perforation.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Autoimmune Diseases / diagnosis
  • Autoimmune Diseases / drug therapy
  • Autoimmune Diseases / etiology*
  • Cornea / pathology*
  • Diagnosis, Differential
  • Female
  • Glucocorticoids / administration & dosage*
  • Humans
  • Phacoemulsification / adverse effects*
  • Postoperative Complications
  • Prednisone / administration & dosage
  • Visual Acuity

Substances

  • Glucocorticoids
  • Prednisone