Donor registries and search strategies

Methods Mol Biol. 2012:882:531-47. doi: 10.1007/978-1-61779-842-9_30.

Abstract

The optimal donor of hematopoietic progenitor cells shares alleles of the major histocompatibility genes with the recipient. This chapter describes the strategies aimed at identifying such a matched donor from registries of volunteers or from umbilical cord blood banks.

MeSH terms

  • Alleles
  • Blood Banks
  • Fetal Blood
  • HLA Antigens / genetics*
  • HLA Antigens / immunology
  • Hematopoietic Stem Cell Transplantation / methods
  • Hematopoietic Stem Cells* / immunology
  • Hematopoietic Stem Cells* / metabolism
  • Histocompatibility Testing*
  • Humans
  • Registries*
  • Tissue and Organ Procurement / methods*
  • Unrelated Donors
  • Volunteers

Substances

  • HLA Antigens