Microbial transformations of 7-hydroxyflavanone

ScientificWorldJournal. 2012:2012:254929. doi: 10.1100/2012/254929. Epub 2012 Apr 30.

Abstract

Microbial transformations of racemic 7-hydroxyflavanone using strains of genus Aspergillus (A. niger KB, A. niger 13/5, A. ochraceus 456) and the species Penicillium chermesinum 113 were studied. The products of O-methylation, O-methylation along with hydroxylation at C-3' and C-4', reduction of the carbonyl group, reduction of the carbonyl group along with hydroxylation at C-5, and dehydrogenation of C-2 and C-3 were obtained. Most of the products (with the exception of the O-methylation one) have stronger antioxidant properties than the initial substrate.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antioxidants / metabolism
  • Aspergillus / metabolism*
  • Flavanones / metabolism*
  • Hydroxylation
  • Penicillium / metabolism*

Substances

  • Antioxidants
  • Flavanones
  • 7-hydroxyflavanone