Novel ecdysteroids from Serratula wolffii

ScientificWorldJournal. 2012:2012:651275. doi: 10.1100/2012/651275. Epub 2012 May 2.

Abstract

Two new and one known ecdysteroids were identified in the methanolic extract of the roots of Serratula wolffii. The new compounds isolated were ponasterone A-22-apioside (1) and 3-epi-shidasterone (3), together with the known 3-epi-22-deoxy-20-hydroxyecdysone (2). The structures of compounds 1-3 were determined by extensive spectroscopic techniques, including one- and two-dimensional NMR methods.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Asteraceae / metabolism*
  • Chemistry, Pharmaceutical / methods
  • Drug Design
  • Ecdysteroids / chemistry*
  • Ecdysterone / analogs & derivatives
  • Ecdysterone / chemistry
  • Glycosides / chemistry
  • Magnetic Resonance Spectroscopy / methods
  • Mass Spectrometry / methods
  • Models, Chemical
  • Plant Extracts / pharmacology
  • Plant Roots / metabolism
  • Spectrophotometry / methods

Substances

  • Ecdysteroids
  • Glycosides
  • Plant Extracts
  • Ecdysterone
  • ponasterone A