Influenza A (H1N1) was not associated with obesity in pregnant women living in Toluca, México

Rev Salud Publica (Bogota). 2011 Dec;13(6):897-907. doi: 10.1590/s0124-00642011000600003.

Abstract

Objective: The aim was to verify whether being overweight could have played a critical role in cases of mortality caused by influenza A (H1N1) in pregnant women. This virus' prevalence was also analyzed among people suffering from acute respiratory disease being attended at the state of Mexico's Autonomous University's medical research centre.

Methods: The clinical files of women having influenza A (H1N1) attending the Monica Pretelini maternal-perinatal hospital's (HMPMP) intensive care unit in Toluca, Mexico, were reviewed. According to international recommendations, clinical detection of possible new cases of this disease was kept an open as a second step.

Results: Five women suffering influenza A (H1N1) was attended at HMPMP's intensive care unit during 2009; only one survived. No differences in body mass index were found when comparing the anthropometric characteristics to another group of women affected by acute respiratory diseases; in fact, this parameter was below the limits for being overweight in both cases. No new case of influenza A (H1N1) was found after the first eight months of 2010.

Discussion: It could not be verified whether being overweight was a factor of higher mortality due to influenza A (H1N1) amongst pregnant women in the state of Mexico. The key to better survival for pregnant women hospitalized with influenza A (H1N1) seemed to be early treatment with oseltamivir. The cases decreased dramatically after the severe wave of the new pandemic due to unknown reasons.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Body Mass Index
  • Comorbidity
  • Cross-Sectional Studies
  • Female
  • Hospitals, Maternity / statistics & numerical data
  • Hospitals, University / statistics & numerical data
  • Humans
  • Influenza A Virus, H1N1 Subtype* / genetics
  • Influenza A Virus, H1N1 Subtype* / isolation & purification
  • Influenza, Human / drug therapy
  • Influenza, Human / epidemiology*
  • Influenza, Human / mortality
  • Male
  • Mexico / epidemiology
  • Obesity / epidemiology
  • Overweight / epidemiology*
  • Pandemics*
  • Pregnancy
  • Pregnancy Complications, Infectious / epidemiology*
  • Pregnancy Complications, Infectious / mortality
  • Pregnancy, High-Risk
  • Prevalence
  • Puerperal Disorders / mortality
  • RNA, Viral / blood
  • Respiration Disorders / epidemiology
  • Respiratory Distress Syndrome / epidemiology
  • Respiratory Distress Syndrome / etiology
  • Retrospective Studies
  • Young Adult

Substances

  • RNA, Viral