In epilepsy, BAD is not really bad

Elena Ziviani; Luca Scorrano

doi:10.1016/j.neuron.2012.05.003

In epilepsy, BAD is not really bad

Neuron. 2012 May 24;74(4):600-2. doi: 10.1016/j.neuron.2012.05.003.

Authors

Elena Ziviani¹, Luca Scorrano

Affiliation

¹ Department of Cell Physiology and Medicine, University of Geneva, 1 Rue M. Servet, 1205 Geneve, Switzerland.

PMID: 22632717
DOI: 10.1016/j.neuron.2012.05.003

Abstract

In this issue of Neuron, Giménez-Cassina et al. (2012) show that fuel utilization by neuronal mitochondria, controlled by the Bcl-2 family member BAD, defines response to seizures. Control of K(ATP) channels by mitochondrial metabolism might be a target for antiepileptic therapies.

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