Antibiotic resistance of Streptococcus agalactiae from cows with mastitis

Vet J. 2012 Dec;194(3):423-4. doi: 10.1016/j.tvjl.2012.04.020. Epub 2012 May 23.

Abstract

The aim of this study was to characterise the phenotypic and genotypic antibiotic resistance patterns of Streptococcus agalactiae isolated from cows with mastitis in China. Antibiotic resistance was based on minimum inhibitory concentrations and detection of resistance genes by PCR. S. agalactiae isolates most frequently exhibited phenotypic resistance to tetracycline, while the resistance genes most frequently detected were ermB, tetL and tetM. Resistance genes were detected in some susceptible isolates, whereas no resistance genes could be detected in some resistant isolates, indicating that the resistance genotype does not accurately predict phenotypic resistance.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amikacin / pharmacology
  • Animals
  • Anti-Bacterial Agents / pharmacology*
  • Bacterial Proteins / genetics*
  • Bacterial Proteins / metabolism
  • Cattle
  • China
  • Drug Resistance, Bacterial*
  • Erythromycin / pharmacology
  • Female
  • Genotype
  • Gentamicins / pharmacology
  • Mastitis, Bovine / microbiology*
  • Microbial Sensitivity Tests / veterinary
  • Penicillin G / pharmacology
  • Phenotype
  • Streptococcus agalactiae / drug effects*
  • Streptococcus agalactiae / genetics*
  • Streptococcus agalactiae / isolation & purification
  • Tetracycline / pharmacology

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • Gentamicins
  • Erythromycin
  • Amikacin
  • Tetracycline
  • Penicillin G