Ultraviolet light-induced changes of lymphatic and blood vasculature in skin and their molecular mechanisms

Exp Dermatol. 2012 Jul:21 Suppl 1:22-5. doi: 10.1111/j.1600-0625.2012.01498.x.

Abstract

Ultraviolet light in the 290- to 320-nm wavelength range (UVB) induces angiogenesis and lymphatic dysfunction in skin. This review deals with UVB-induced alterations to the blood and lymphatic systems in skin and the molecular mechanisms involved. We also discuss potential strategies to block photoageing of skin by inhibiting angiogenesis and/or promoting lymphatic vascular function.

Publication types

  • Review

MeSH terms

  • Animals
  • Blood Vessels / pathology*
  • Blood Vessels / radiation effects
  • Humans
  • Light
  • Lymphatic System
  • Lymphatic Vessels / pathology*
  • Lymphatic Vessels / radiation effects
  • Mice
  • Models, Biological
  • Neovascularization, Physiologic / radiation effects
  • Signal Transduction
  • Skin / blood supply*
  • Skin / pathology
  • Skin / radiation effects
  • Skin Aging / radiation effects*
  • Ultraviolet Rays