The girls and boys (the ethnic tofs) residing in the village of Alykdjer of Nijneudinsky district of Irkutsk oblast have been examined. The Irkutsk girls and boys (the Caucasians) made the comparison groups. In tof boys the activation of hypophyseal-thyroid system and activity increase of lipoprotein spectrum of blood serum was established. Furthermore, in the tof adolescents the level of liposoluble vitamin alpha-tocopherol is increased as compared with the Caucasians adolescents.