Interventional therapies for lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH)

Minerva Urol Nefrol. 2012 Jun;64(2):123-33.

Abstract

Benign prostatic hyperplasia (BPH) is a common disease in older men that can lead to lower urinary tract symptoms (LUTS). After failure of medical treatment, surgical managements has to be considered. Surgical management of lower urinary tract symptoms attributed to BPH has progressed over time as urologic surgeons search for more innovative and less invasive forms of treatment. Transurethral resection of the prostate (TURP) has long been the "gold standard" to which all other forms of treatment are compared. There are several different methods of surgical treatment of BPH, including whole gland enucleation, laser vaporization, and induction of necrosis with delayed reabsorption as well as hybrid techniques. As with any form of surgical intervention, long-term results define success. Long-term follow-up consists of examining overall efficacy with attention to associated adverse events. TURP has the luxury of the longest follow-up, while less invasive forms of treatment starting to acquire long-term data. There are several surgical options for BPH; newer methods do show promise, while the "gold standard" continues to demonstrate excellent surgical results.

MeSH terms

  • Age Factors
  • Botulinum Toxins, Type A / therapeutic use
  • Humans
  • Laser Therapy / methods
  • Lower Urinary Tract Symptoms / etiology
  • Lower Urinary Tract Symptoms / surgery*
  • Lower Urinary Tract Symptoms / therapy
  • Male
  • Prostatic Hyperplasia / surgery*
  • Prostatic Hyperplasia / therapy
  • Prostatism / surgery
  • Quality of Life
  • Randomized Controlled Trials as Topic
  • Risk Factors
  • Transurethral Resection of Prostate / methods*
  • Transurethral Resection of Prostate / trends
  • Treatment Outcome

Substances

  • Botulinum Toxins, Type A