False-positive Aspergillus antigenemia due to blood product conditioning fluids

Clin Infect Dis. 2012 Aug;55(4):e22-7. doi: 10.1093/cid/cis493. Epub 2012 May 18.

Abstract

The presence of Aspergillus antigens in blood transfusion components from different manufacturers was analyzed. Galacomannans were found in transfused patients, pooled platelet concentrates, fresh frozen plasma, and packed red cells collected using Fresenius Kabi bags. Galacomannans were also found in blood collection anticoagulant and platelet additive solution from this manufacturer.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Antigens, Fungal / blood*
  • Aspergillosis / blood*
  • Aspergillosis / diagnosis
  • Aspergillus / isolation & purification*
  • Cytomegalovirus Infections / blood
  • Cytomegalovirus Infections / diagnosis
  • False Positive Reactions
  • Female
  • Fungemia / blood*
  • Fungemia / diagnosis
  • Galactose / analogs & derivatives
  • Humans
  • Mannans / blood
  • Platelet Transfusion / adverse effects*

Substances

  • Antigens, Fungal
  • Mannans
  • galactomannan
  • Galactose