Longitudinal MRI study of the pituitary volume in chronic schizophrenia: a preliminary report

Tsutomu Takahashi; Mikio Kido; Kazue Nakamura; Atsushi Furuichi; Shi-Yu Zhou; Yasuhiro Kawasaki; Kyo Noguchi; Hikaru Seto; Masayoshi Kurachi; Michio Suzuki

doi:10.1016/j.pscychresns.2011.11.008

Longitudinal MRI study of the pituitary volume in chronic schizophrenia: a preliminary report

Psychiatry Res. 2012 Apr 30;202(1):84-7. doi: 10.1016/j.pscychresns.2011.11.008. Epub 2012 May 16.

Authors

Tsutomu Takahashi¹, Mikio Kido, Kazue Nakamura, Atsushi Furuichi, Shi-Yu Zhou, Yasuhiro Kawasaki, Kyo Noguchi, Hikaru Seto, Masayoshi Kurachi, Michio Suzuki

Affiliation

¹ Department of Neuropsychiatry, University of Toyama, Toyama, Japan. tsutomu@med.u-toyama.ac.jp

PMID: 22608154
DOI: 10.1016/j.pscychresns.2011.11.008

Abstract

This longitudinal MRI study investigated the pituitary volume in 17 patients with chronic schizophrenia and 17 matched controls. In contrast to previous findings of pituitary expansion during the first episode of schizophrenia, the chronic patients showed non-significant mild pituitary atrophy, suggesting that the pituitary volume changes differently at different illness stages.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Atrophy / pathology
Disease Progression
Female
Humans
Longitudinal Studies
Magnetic Resonance Imaging
Male
Middle Aged
Organ Size
Pituitary Gland / pathology*
Schizophrenia / pathology*