Molecular epidemiology of Laguna Negra virus, Mato Grosso State, Brazil

Elizabeth S Travassos da Rosa; Daniele B A Medeiros; Márcio R T Nunes; Darlene B Simith; Armando de S Pereira; Mauro R Elkhoury; Elizabeth Davi Santos; Marília Lavocat; Aparecido A Marques; Alba V G Via; Vânia A Kohl; Ana C P Terças; Paulo D'Andrea; Cibele R Bonvícino; Elba R Sampaio de Lemos; Pedro F C Vasconcelos

doi:10.3201/eid1806.110948

Molecular epidemiology of Laguna Negra virus, Mato Grosso State, Brazil

Emerg Infect Dis. 2012 Jun;18(6):982-5. doi: 10.3201/eid1806.110948.

Authors

Elizabeth S Travassos da Rosa¹, Daniele B A Medeiros, Márcio R T Nunes, Darlene B Simith, Armando de S Pereira, Mauro R Elkhoury, Elizabeth Davi Santos, Marília Lavocat, Aparecido A Marques, Alba V G Via, Vânia A Kohl, Ana C P Terças, Paulo D'Andrea, Cibele R Bonvícino, Elba R Sampaio de Lemos, Pedro F C Vasconcelos

Affiliation

¹ Evandro Chagas Institute, Ministry of Health, Ananindeua, Brazil.

Abstract

We associated Laguna Negra virus with hantavirus pulmonary syndrome in Mato Grosso State, Brazil, and a previously unidentified potential host, the Calomys callidus rodent. Genetic testing revealed homologous sequencing in specimens from 20 humans and 8 mice. Further epidemiologic studies may lead to control of HPS in Mato Grosso State.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Arvicolinae
Bayes Theorem
Brazil / epidemiology
Genetic Variation
Hantavirus Pulmonary Syndrome / epidemiology
Hantavirus Pulmonary Syndrome / veterinary*
Hantavirus Pulmonary Syndrome / virology
Humans
Likelihood Functions
Mice
Multilocus Sequence Typing
Nucleocapsid Proteins / genetics
Orthohantavirus / classification
Orthohantavirus / genetics*
Phylogeny
Rodent Diseases / epidemiology
Rodent Diseases / virology*

Substances

Nucleocapsid Proteins