In the mol-ecule of the title compound, C(31)H(36)N(2)O(5), the piperazine ring displays a chair conformation. The dihedral angle between the benzene rings of the bis-(4-meth-oxy-phen-yl)methyl group is 83.42 (15)°. In the crystal, centrosymmetric-ally related mol-ecules are linked through pairs of C-H⋯O hydrogen bonds into dimers, generating an R(2) (2)(10) ring motif. The dimers are further connected into chains parallel to [2-10] by C-H⋯O hydrogen bonds involving the meth-oxy groups.