Extra-pulmonary primary multidrug-resistant tubercular lymphadenitis in an HIV negative patient

BMJ Case Rep. 2012 May 8:2012:bcr0620114337. doi: 10.1136/bcr.06.2011.4337.

Abstract

A 28-year-old woman without any history of prior antituberculosis treatment presented with cervical lymphadenopathy and a cold abscess near medial end of clavicle of 5 months duration. Pus culture and sensitivity revealed Mycobacterium tuberculosis resistant to rifampicin and isoniazid. Thus she was diagnosed as a case of primary multidrug-resistant tuberculosis and treated with second line drugs according to culture susceptibility pattern. On completion of therapy, patent showed good clinical response. This case highlights the observation that even extra-pulmonary primary multidrug-resistant tuberculosis can be successfully treated with currently available second line drugs.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antitubercular Agents / therapeutic use*
  • Clarithromycin / therapeutic use
  • Clofazimine / therapeutic use
  • Cycloserine / therapeutic use
  • Diagnosis, Differential
  • Drug Therapy, Combination
  • Ethambutol / therapeutic use
  • Ethionamide / therapeutic use
  • Female
  • HIV Seronegativity
  • Humans
  • Isoniazid / therapeutic use
  • Kanamycin / therapeutic use
  • Ofloxacin / therapeutic use
  • Pyrazinamide / therapeutic use
  • Rifampin / therapeutic use
  • Tuberculosis, Lymph Node / diagnosis*
  • Tuberculosis, Lymph Node / drug therapy*
  • Tuberculosis, Multidrug-Resistant / diagnosis*
  • Tuberculosis, Multidrug-Resistant / drug therapy*

Substances

  • Antitubercular Agents
  • Pyrazinamide
  • Kanamycin
  • Ethambutol
  • Cycloserine
  • Ofloxacin
  • Clofazimine
  • Clarithromycin
  • Ethionamide
  • Isoniazid
  • Rifampin