Experimental measurements and Monte Carlo calculations for (103)Pd dosimetry of the 12 mm COMS eye plaque

Phys Med. 2013 May;29(3):286-94. doi: 10.1016/j.ejmp.2012.04.002. Epub 2012 May 14.

Abstract

Monte Carlo simulations and TLD dosimetry have been performed to determine the dose distributions along the central axis of the 12 mm COMS eye plaques loaded with IRA1-(103)Pd seeds. Several simulations and measurements have been employed to investigate the effect of Silastic insert and air in front of the eye on dosimetry results along the central axis of the plaque and at some critical ocular structures. Measurements were performed using TLD-GR200A circular chip dosimeters in a PMMA eye phantom. The central axis TLD chips locations were arranged in one central column of eye phantom, in 3 mm intervals. The off-axis TLD chips locations were arranged in three off-axis columns around the central axis column. Version 5 of the MCNP code was also used to evaluate the dose distribution around the plaque. The presence of the Silastic insert results in dose reduction of 14% at 5 mm; also about 7% dose reduction appears at the interface point, due to the air presence and lack of the scattering condition. The overall dosimetric parameters for the COMS eye plaque loaded with new palladium seeds are similar to a commercial widely used seed such as Theragenics200. As the dose calculations under TG-43 assumptions do not consider the effect of the plaque backing and Silastic insert for accurate dosimetry, it's suggested to apply the effect of the eye plaque materials and air on dosimetry results along the central axis of the plaque and at some critical ocular structures.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brachytherapy / instrumentation*
  • Brachytherapy / methods
  • Choroid Neoplasms / radiotherapy*
  • Equipment Design
  • Equipment Failure Analysis
  • Eye, Artificial*
  • Humans
  • Monte Carlo Method
  • Palladium / analysis*
  • Radiometry / methods*
  • Radiotherapy Dosage
  • Reproducibility of Results
  • Sensitivity and Specificity

Substances

  • Palladium