Toward biodegradable nanogel star polymers via organocatalytic ROP

Eric A Appel; Victor Y Lee; Timothy T Nguyen; Melanie McNeil; Frederik Nederberg; James L Hedrick; William C Swope; Jullia E Rice; Robert D Miller; Joseph Sly

doi:10.1039/c2cc31406a

Toward biodegradable nanogel star polymers via organocatalytic ROP

Chem Commun (Camb). 2012 Jun 21;48(49):6163-5. doi: 10.1039/c2cc31406a. Epub 2012 May 16.

Authors

Eric A Appel¹, Victor Y Lee, Timothy T Nguyen, Melanie McNeil, Frederik Nederberg, James L Hedrick, William C Swope, Jullia E Rice, Robert D Miller, Joseph Sly

Affiliation

¹ IBM Almaden Research Center, 650 Harry Road, San Jose, CA 95120, USA.

PMID: 22590707
DOI: 10.1039/c2cc31406a

Abstract

Organocatalytic ring opening polymerization (OROP) is used to effect the rapid, scalable, room temperature formation of size-controlled, highly uniform, polyvalent, nanogel star polymer nanoparticles of biodegradable composition.

MeSH terms

Bridged Bicyclo Compounds, Heterocyclic / chemistry*
Catalysis
Models, Molecular
Molecular Structure
Nanogels
Polyethylene Glycols / chemistry
Polyethylene Glycols / metabolism*
Polyethyleneimine / chemistry
Polyethyleneimine / metabolism*
Polymerization
Polymers / chemistry
Polymers / metabolism*

Substances

Bridged Bicyclo Compounds, Heterocyclic
Nanogels
Polymers
polyethylene glycol polyethyleneimine nanogel
Polyethylene Glycols
Polyethyleneimine