Morphologic analysis in pathologic myopia using high-penetration optical coherence tomography

Invest Ophthalmol Vis Sci. 2012 Jun 20;53(7):3834-8. doi: 10.1167/iovs.12-9811.

Abstract

Purpose: We evaluated retrospectively the morphologic choroidal and scleral characteristics in eyes with pathologic myopia using high-penetration optical coherence tomography (HP-OCT) or swept-source OCT (SS-OCT).

Methods: The subfoveal choroidal and scleral thicknesses were measured using the prototype HP-OCT with a 1060 nm light source. We also measured the scleral thickness 3 mm superior, inferior, nasal, and temporal to the fovea on the horizontal and vertical OCT sections. The axial length (AL) in all eyes was measured using optical biometry.

Results: We examined 58 eyes of 35 patients (7 men and 28 women, mean age 65.5 years) with an AL exceeding 26.5 mm. The mean AL was 29.0 ± 1.4 mm. The full-thickness choroid and sclera were visualized in all eyes. The mean subfoveal choroidal and scleral thicknesses were 52 ± 38 and 335 ± 130 μm, respectively. The mean scleral thicknesses 3 mm superior, inferior, nasal, and temporal to the fovea were 266 ± 78 (n = 57), 259 ± 72 (n = 56), 324 ± 109 (n = 39), and 253 ± 79 (n = 58) μm, respectively. The subfoveal sclera was thicker than 3 mm outside the fovea (P < 0.05, for each comparison).

Conclusions: The full-thickness choroid and sclera in all eyes with pathologic myopia were visualized using a prototype HP-OCT. The subfoveal sclera was thicker than 3 mm outside the fovea. HP-OCT is a useful tool for morphologic analyses of pathologic myopia.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Choroid / pathology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myopia, Degenerative / pathology*
  • Retrospective Studies
  • Sclera / pathology*
  • Tomography, Optical Coherence / methods*