Kinase inhibitors for advanced medullary thyroid carcinoma

Clinics (Sao Paulo). 2012;67 Suppl 1(Suppl 1):125-9. doi: 10.6061/clinics/2012(sup01)21.

Abstract

The recent availability of molecular targeted therapies leads to a reconsideration of the treatment strategy for patients with distant metastases from medullary thyroid carcinoma. In patients with progressive disease, treatment with kinase inhibitors should be offered.

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents / adverse effects
  • Antineoplastic Agents / therapeutic use*
  • Carcinoma, Medullary / drug therapy*
  • Carcinoma, Medullary / pathology
  • Carcinoma, Neuroendocrine
  • Clinical Trials as Topic / standards
  • Humans
  • Molecular Targeted Therapy
  • Patient Selection
  • Piperidines / adverse effects
  • Piperidines / therapeutic use*
  • Protein Kinase Inhibitors / therapeutic use*
  • Quinazolines / adverse effects
  • Quinazolines / therapeutic use*
  • Thyroid Neoplasms / drug therapy*
  • Thyroid Neoplasms / secondary

Substances

  • Antineoplastic Agents
  • Piperidines
  • Protein Kinase Inhibitors
  • Quinazolines
  • vandetanib

Supplementary concepts

  • Thyroid cancer, medullary