Monotherapy with pefloxacin in multidrug-resistant nosocomial gram-negative bacteraemia

J Antimicrob Chemother. 1990 Oct:26 Suppl B:91-5. doi: 10.1093/jac/26.suppl_b.91.

Abstract

Twenty patients who developed nosocomial Gram-negative bacteraemias in the medical or surgical intensive care units were treated with pefloxacin. All organisms were susceptible to pefloxacin and had not responded to previous antimicrobial therapy. The bacteraemias were eradicated in 16 of the 20 patients, all of whom tolerated the therapy without adverse effects.

Publication types

  • Clinical Trial

MeSH terms

  • Administration, Oral
  • Adult
  • Aged
  • Cross Infection / drug therapy*
  • Drug Resistance, Microbial
  • Female
  • Humans
  • Infusions, Intravenous
  • Male
  • Middle Aged
  • Pefloxacin / administration & dosage
  • Pefloxacin / therapeutic use*
  • Pneumonia / complications
  • Pseudomonas Infections / complications
  • Pseudomonas Infections / drug therapy
  • Sepsis / complications
  • Sepsis / drug therapy*

Substances

  • Pefloxacin