Efficacy of fibrinogen/thrombin-coated equine collagen patch in controlling lymphatic leaks

J Card Surg. 2012 Jul;27(4):441-2. doi: 10.1111/j.1540-8191.2012.01461.x. Epub 2012 May 14.

Abstract

We report the use of fibrinogen/thrombin-coated equine collagen patch (Tachosil(®) ) as a sealant agent in six patients who underwent heart surgery for congenital heart disease (CHD) and developed an intraoperative lymphatic leakage detected at the time of surgery. The use of fibrinogen/thrombin-coated equine collagen patch proved to be safe and effective in preventing the development of postoperative chylothorax.

Publication types

  • Evaluation Study

MeSH terms

  • Child, Preschool
  • Chylothorax / etiology
  • Chylothorax / prevention & control*
  • Drug Combinations
  • Fibrinogen / therapeutic use*
  • Follow-Up Studies
  • Heart Defects, Congenital / surgery*
  • Humans
  • Infant
  • Intraoperative Complications / therapy*
  • Lymphatic Vessels / injuries*
  • Lymphatic Vessels / pathology
  • Postoperative Complications / prevention & control*
  • Surgical Sponges*
  • Thrombin / therapeutic use*
  • Treatment Outcome

Substances

  • Drug Combinations
  • TachoSil
  • Fibrinogen
  • Thrombin