Chemical analysis and antioxidant activity in vitro of a β-D-glucan isolated from Dictyophora indusiata

Int J Biol Macromol. 2012 Jul-Aug;51(1-2):70-5. doi: 10.1016/j.ijbiomac.2012.05.001. Epub 2012 May 8.

Abstract

In this study, a water-soluble polysaccharide (PPS) from Dictyophora indusiata was purified and investigated through a combination of gel chromatography (Sephadex G-200), infrared (IR) spectroscopy, and gas chromatography-mass spectrometry (GC-MS). The results indicated that PPS has a backbone of β-conformation, mainly consist of glucose (98.58%). And the antioxidant activities of PPS were investigated in vitro including reducing power, hydroxyl assay, superoxide radical assay and DPPH scavenge activity. The results showed that PPS has antioxidant activities in all these assay systems, suggesting it may be explored as a novel natural antioxidant with potential therapeutic properties in mammalian systems.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antioxidants / chemistry*
  • Antioxidants / isolation & purification
  • Basidiomycota / chemistry*
  • Free Radical Scavengers / chemistry
  • Superoxides / chemistry
  • beta-Glucans / chemistry*
  • beta-Glucans / isolation & purification

Substances

  • Antioxidants
  • Free Radical Scavengers
  • beta-Glucans
  • Superoxides