Applications of NMR in the characterization of pharmaceutical microemulsions

J Control Release. 2012 Jul 10;161(1):62-72. doi: 10.1016/j.jconrel.2012.04.032. Epub 2012 May 1.

Abstract

Microemulsions have successfully proven themselves as useful vehicles for drugs through the different routes of administration because they can confer on drugs greater water solubility and bioavailability. The ability to understand the structural aspects of these important drug delivery systems is essential to the progress of this science. The use of NMR techniques in pharmaceutical and drug delivery science is increasing especially in the characterization field. This review demonstrates the major and novel NMR methods and techniques used in understanding and characterizing the different microemulsion components, types and structures.

Publication types

  • Review

MeSH terms

  • Drug Delivery Systems*
  • Emulsions / chemistry*
  • Magnetic Resonance Spectroscopy / methods*
  • Pharmaceutical Preparations / administration & dosage
  • Pharmaceutical Preparations / chemistry

Substances

  • Emulsions
  • Pharmaceutical Preparations