Abstract
The pentatricopeptide repeat (PPR) protein family is highly expanded in terrestrial plants. Arabidopsis contains 450 PPR genes, which represents 2% of the total protein-coding genes. PPR proteins are eukaryote-specific RNA-binding proteins implicated in multiple aspects of RNA metabolism of organellar genes. Most PPR proteins affect a single or small subset of gene(s), acting in a gene-specific manner. Studies over the last 10 years have revealed the significance of this protein family in coordinated gene expression in different compartments: the nucleus, chloroplast and mitochondrion. Here, we summarize recent studies addressing the mechanistic aspect of PPR proteins.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Amino Acid Motifs
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Amino Acid Substitution
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Arabidopsis / genetics
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Arabidopsis / metabolism*
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Arabidopsis Proteins / genetics
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Arabidopsis Proteins / metabolism*
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Chloroplasts / genetics
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Chloroplasts / metabolism
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Gene Expression Regulation, Plant
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Genes, Plant
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Mitochondria / genetics
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Mitochondria / metabolism
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RNA / genetics
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RNA / metabolism*
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RNA Editing
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RNA, Mitochondrial
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RNA, Plant / genetics
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RNA, Plant / metabolism*
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RNA-Binding Proteins / genetics
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RNA-Binding Proteins / metabolism*
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Species Specificity
Substances
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Arabidopsis Proteins
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RNA, Mitochondrial
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RNA, Plant
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RNA-Binding Proteins
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pentatricopeptide repeat protein, Arabidopsis
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RNA