Through the National Center for Integrated Civilian-Military Domestic Disaster Medical Response, the Yale New Haven Center for Emergency Preparedness and Disaster Response and US Northern Command have initiated a study to determine the requirements of a national operational epidemiological modelling process. During a public health emergency, decision makers often require a variety of epidemiological information, including prospective forecasts that can be made available in the form of models. Currently, there is no formal process across US Government agencies and departments to synchronise epidemiological models with response organisations. The research presented here summarises the landscape of the modelling and consequence management communities for the purpose of informing the development of a proposed national operational epidemiological modelling process.