Insulin therapy in pregnancy

Endocrinol Metab Clin North Am. 2012 Mar;41(1):161-73. doi: 10.1016/j.ecl.2011.12.002. Epub 2012 Jan 4.

Abstract

Insulin therapy is essential for optimal glycemic control during pregnancy in women with type 1 diabetes and is frequently required to optimize control in women with type 2 diabetes. Less commonly, women with gestational diabetes mellitus (GDM) require insulin for glycemic control. However, because of its greater prevalence, GDM is the most common reason for insulin use in pregnancy. The most frequently used insulin regimen in pregnancy is a basal/bolus combination of long- and short-acting insulin preparations. There is no evidence base to support one treatment regimen over another. Therapy should be individualized and based on local expertise.

Publication types

  • Review

MeSH terms

  • Blood Glucose
  • Diabetes Mellitus, Type 1 / blood
  • Diabetes Mellitus, Type 1 / drug therapy*
  • Female
  • Humans
  • Hypoglycemic Agents / therapeutic use*
  • Insulin / therapeutic use*
  • Pregnancy
  • Pregnancy in Diabetics / blood
  • Pregnancy in Diabetics / drug therapy*

Substances

  • Blood Glucose
  • Hypoglycemic Agents
  • Insulin