This Statistical Brief presents data from the Healthcare Cost and Utilization Project (HCUP) Nationwide Inpatient Sample on hospital stays for cancer care among adults age 18 and older in 2009. Characteristics of these stays are compared by type of cancer and compared with adult hospitalizations for all other conditions. The most common cancer hospitalizations are identified and trends in the number of stays from 2000 to 2009 are displayed. Stays with a secondary diagnosis of cancer are enumerated, and the most frequent principal diagnoses for these stays are noted. All differences between estimates noted in the text are statistically significant at the 0.05 level or better.