Synthesis, Binding and Fluorescence Studies of Bis-2-amidopyrrole Receptors for Bis-carboxylate Anions

Belén Jiménez; Emilio Calle; Cruz Caballero

doi:10.3390/s90301534

Synthesis, Binding and Fluorescence Studies of Bis-2-amidopyrrole Receptors for Bis-carboxylate Anions

Sensors (Basel). 2009;9(3):1534-40. doi: 10.3390/s90301534. Epub 2009 Mar 4.

Authors

Belén Jiménez¹, Emilio Calle, Cruz Caballero

Affiliation

¹ Organic Chemistry Department, Plaza de los Caidos, 1-5, University of Salamanca, E-37008 Salamanca, Spain; E-Mail: belenjj@yahoo.es.

Abstract

The ditopic neutral receptors 1 and 2 were synthesized for the recognition and sensing of bis-carboxylates. They are based on pyrrole and amide groups as hydrogen-bond donors to bind the oxoanions of the guests. Among the obtained results, the selectivity for glutarate over succinate is particularly interesting. Compound 1 behaves as a PET fluorescence sensor for glutarate.

Keywords: Molecular recognition; bis-2-amidopyrrole receptors; bis-carboxylate anions; fluorescent sensor; hydrogen bonding.