Tetralogy of Fallot with Holt-Oram syndrome

Indian Heart J. 2012 Jan-Feb;64(1):95-8. doi: 10.1016/S0019-4832(12)60021-2. Epub 2012 Mar 26.

Abstract

Holt-Oram syndrome (HOS) is characterised by mild to severe congenital cardiac defects and skeletal abnormalities of the upper limb. This syndrome is also referred to as Hand-Heart syndrome. The most common cardiac disorder is an ostium secundum detected an atrial septal defect (ASD), followed by ventricular septal defect (VSD) and ostium primum ASD. We report a case of HOS with tetralogy of Fallot (TOF). This association is very rare and is hardly reported in the literature.

Publication types

  • Case Reports

MeSH terms

  • Abnormalities, Multiple / diagnosis
  • Child, Preschool
  • Echocardiography, Doppler
  • Electrocardiography
  • Female
  • Heart Defects, Congenital / complications*
  • Heart Defects, Congenital / diagnosis
  • Heart Septal Defects, Atrial / complications*
  • Heart Septal Defects, Atrial / diagnosis
  • Humans
  • Lower Extremity Deformities, Congenital / complications*
  • Lower Extremity Deformities, Congenital / diagnosis
  • Tetralogy of Fallot / complications*
  • Tetralogy of Fallot / diagnosis
  • Upper Extremity Deformities, Congenital / complications*
  • Upper Extremity Deformities, Congenital / diagnosis

Supplementary concepts

  • Holt-Oram syndrome