Complete genome sequence of two novel Chinese virulent porcine reproductive and respiratory syndrome virus variants

J Virol. 2012 Jun;86(11):6373-4. doi: 10.1128/JVI.00663-12.

Abstract

A highly pathogenic strain of porcine reproductive and respiratory syndrome virus (PRRSV), characterized by a discontinuous 30-amino-acid deletion in its Nsp2-coding region, has been emerging in China since 2006. Here, we report the complete genomic sequence of two novel Chinese virulent PRRSV variants with additional NSP2-gene deletions, which will help us understand the molecular and evolutionary characteristics of PRRSV in Asia.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Base Sequence
  • China
  • Genome, Viral*
  • Molecular Sequence Data
  • Porcine Reproductive and Respiratory Syndrome / pathology
  • Porcine Reproductive and Respiratory Syndrome / virology*
  • Porcine respiratory and reproductive syndrome virus / genetics*
  • Porcine respiratory and reproductive syndrome virus / isolation & purification*
  • RNA, Viral / genetics*
  • Sequence Alignment
  • Sequence Analysis, DNA*
  • Sequence Deletion
  • Swine / virology*
  • Viral Nonstructural Proteins / genetics
  • Virulence

Substances

  • RNA, Viral
  • Viral Nonstructural Proteins

Associated data

  • GENBANK/JQ715697
  • GENBANK/JQ715698