PARP-1 and cytokine-mediated β-cell damage: a nick in the Okamoto model?

Am J Physiol Endocrinol Metab. 2012 Jul 15;303(2):E170-1. doi: 10.1152/ajpendo.00226.2012. Epub 2012 May 8.
No abstract available

Publication types

  • Editorial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cytokines / metabolism*
  • DNA Breaks / drug effects
  • Diabetes Mellitus, Experimental / metabolism
  • Diabetes Mellitus, Type 1 / chemically induced
  • Diabetes Mellitus, Type 1 / metabolism
  • Humans
  • Insulin-Secreting Cells / metabolism*
  • Mice
  • Poly (ADP-Ribose) Polymerase-1
  • Poly(ADP-ribose) Polymerases / metabolism*

Substances

  • Cytokines
  • PARP1 protein, human
  • Parp1 protein, mouse
  • Poly (ADP-Ribose) Polymerase-1
  • Poly(ADP-ribose) Polymerases