A hospital policy change toward delayed cord clamping is effective in improving hemoglobin levels and anemia status of 8-month-old Peruvian infants

J Trop Pediatr. 2012 Dec;58(6):435-40. doi: 10.1093/tropej/fms012. Epub 2012 May 7.

Abstract

Objective: To assess the effectiveness of a hospital policy change toward delayed cord clamping on infant hemoglobin (Hb) levels and anemia status at 4 and 8 months of age.

Methods: A cohort of Peruvian mothers and infants, originating from a pre/post study investigating a change in hospital policy from early to delayed cord clamping, was followed until 8 months postpartum. Infant hemoglobin levels and anemia status were measured at 4 and 8 months postpartum.

Results: Following the hospital policy change, adjusted mean infant Hb levels improved by 0.89 gdl(-1) [95% confidence interval (95% CI) 0.57-1.22] and anemia was significantly reduced (aOR = 0.38; 95% CI 0.19-0.78) at 8 months postpartum.

Conclusions: A hospital policy change toward delayed cord clamping is effective in improving Hb levels and the anemia status of 8-month-old infants. Prior to scaling-up this intervention, issues related to training, monitoring, safety, additional long-term benefits and specific local conditions should be investigated.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anemia, Iron-Deficiency / blood*
  • Anemia, Iron-Deficiency / prevention & control
  • Anemia, Neonatal / blood*
  • Anemia, Neonatal / prevention & control
  • Confidence Intervals
  • Constriction
  • Delivery, Obstetric
  • Erythrocyte Indices
  • Follow-Up Studies
  • Humans
  • Infant, Newborn
  • Logistic Models
  • Organizational Policy*
  • Peru
  • Time Factors
  • Umbilical Cord / blood supply*