Chemical biology techniques unlock the secrets of casein kinase 2 regulation by phosphorylation and glycosylation

Chembiochem. 2012 Jun 18;13(9):1253-5. doi: 10.1002/cbic.201200235. Epub 2012 May 3.

Abstract

The key to understanding: The application of expressed protein ligation and protein microarrays enabled an unparalleled insight into the complex interaction of phosphorylation and glycosylation on casein kinase 2 and its biological outcome.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biology / methods*
  • Casein Kinase II / chemistry
  • Casein Kinase II / metabolism*
  • Chemistry / methods*
  • Glycosylation
  • Humans
  • Phosphorylation

Substances

  • Casein Kinase II