Effect of CO(2) laser sclerectomy with iridectomy on ocular hypertension in rabbits

Zhi-Xiao Xue; Ying-Xin Li; Yan-Shan Xu; Jiu-Min Yang

doi:10.3980/j.issn.2222-3959.2011.01.06

Effect of CO(2) laser sclerectomy with iridectomy on ocular hypertension in rabbits

Int J Ophthalmol. 2011;4(1):30-2. doi: 10.3980/j.issn.2222-3959.2011.01.06. Epub 2011 Feb 18.

Authors

Zhi-Xiao Xue¹, Ying-Xin Li, Yan-Shan Xu, Jiu-Min Yang

Affiliation

¹ Laser Medicine Laboratory of Tianjin Medical University, Tianjin 300070, China.

PMID: 22553603
PMCID: PMC3340671
DOI: 10.3980/j.issn.2222-3959.2011.01.06

Abstract

Aim: To evaluate the efficiency and safety of an optimized CO(2) Laser glaucoma surgery system for laser sclerectomy with iridectomy.

Methods: Rabbit trials were performed to evaluate the efficiency and safety.

Results: IOP was significantly decreased in laser group compared with trabeculectomy group(P<0.05) from 7(th) postoperative day to 60(th) day. Compared with trabeculectomy group, histopathology studies confirmed fewer complications and better effects were found in laser group.

Conclusion: CO(2) laser sclerectomy with iridectomy is effective and safe in terms of IOP lowering.

Keywords: CO2 laser; glaucoma; histopathological examination; intraocular pressure; sclerectomy with iridectomy.