Quantitative imaging of nonlinear shear modulus by combining static elastography and shear wave elastography

IEEE Trans Ultrason Ferroelectr Freq Control. 2012 Apr;59(4):833-9. doi: 10.1109/TUFFC.2012.2262.

Abstract

The study of new tissue mechanical properties such as shear nonlinearity could lead to better tissue characterization and clinical diagnosis. This work proposes a method combining static elastography and shear wave elastography to derive the nonlinear shear modulus by applying the acoustoelasticity theory in quasi-incompressible soft solids. Results demonstrate that by applying a moderate static stress at the surface of the investigated medium, and by following the quantitative evolution of its shear modulus, it is possible to accurately and quantitatively recover the local Landau (A) coefficient characterizing the shear nonlinearity of soft tissues.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cattle
  • Computer Simulation
  • Elastic Modulus
  • Elasticity Imaging Techniques / instrumentation
  • Elasticity Imaging Techniques / methods*
  • Image Processing, Computer-Assisted / methods*
  • Models, Biological
  • Nonlinear Dynamics
  • Phantoms, Imaging
  • Signal Processing, Computer-Assisted